PKD1 Antibody

Catalog Number:

36876

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q15139
NCBI Gene ID: 5587
Gene Accssion: NP_001009944

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human polycystic kidney disease 1 (autosomal dominant)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PKD1 protein.

Applications:

IHC

Background:

This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1).?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF