TRPM1 Antibody

Catalog Number:

36874

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q7Z4N2
NCBI Gene ID: 4308
Gene Accssion: NP_002411/Q7Z4N2

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human transient receptor potential cation channel, subfamily M, member 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TRPM1 protein.

Applications:

IHC

Background:

This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF