FOXN1 Antibody

Catalog Number:

36869

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O15353
NCBI Gene ID: 8456
Gene Accssion: NP_003584

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human forkhead box N1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FOXN1 protein.

Applications:

IHC

Background:

Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF