FOXL2 Antibody

Catalog Number:

36868

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P58012
NCBI Gene ID: 668
Gene Accssion: NP_075555

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human forkhead box L2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FOXL2 protein.

Applications:

WB

Background:

This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF