FLG Antibody

Catalog Number:

36854

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P20930
NCBI Gene ID: 2312
Gene Accssion: NP_002007

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human filaggrin

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FLG protein.

Applications:

IHC

Background:

The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF