FBN1 Antibody

Catalog Number:

36851

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P35555
NCBI Gene ID: 2200
Gene Accssion: NP_000129

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human fibrillin 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FBN1 protein.

Applications:

IHC

Background:

This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF