MAPK1/MAPK3 Antibody

Catalog Number:

36846

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P28482
NCBI Gene ID: 5594
Gene Accssion: NP_002736/NP_002737

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human mitogen-activated protein kinase 1/2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAPK1/MAPK3 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Datasheet PDF