PTGER4 Antibody

Catalog Number:

36843

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P35408
NCBI Gene ID: 5734
Gene Accssion: NP_000949

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human prostaglandin E receptor 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PTGER4 protein.

Applications:

WB

Background:

The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF