EPCAM Antibody

Catalog Number:

36842

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P16422
NCBI Gene ID: 4072
Gene Accssion: NP_002345

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human epithelial cell adhesion molecule

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EPCAM protein.

Applications:

IHC

Background:

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. EpCAM is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signalling and polarity. It has been used as an immunotherapeutic target in the treatment of gastrointestinal, urological and other carcinomas. It is expressed in undifferentiated pluripotent stem cells.tufting enteropathy.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF