EGFR Antibody

Catalog Number:

36836

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P00533
NCBI Gene ID: 1956
Gene Accssion: NP_005219

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human epidermal growth factor receptor

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EGFR protein.

Applications:

WB

Background:

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF