CXCR1 Antibody

Catalog Number:

36814

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P25024
NCBI Gene ID: 3577
Gene Accssion: NP_000625

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human chemokine (C-X-C motif) receptor 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CXCR1 protein.

Applications:

WB

Background:

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF