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HRK Antibody

Catalog Number:

37633
other_names: DP5; HARAKIRI

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O00198
NCBI Gene ID: 8739
Gene Accssion: NP_003797

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human harakiri, BCL2 interacting protein (contains only BH3 domain)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HRK protein.

Applications:

IHC

Background:

This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

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