COX18 Antibody

Catalog Number:

36801

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8N8Q8
NCBI Gene ID: 285521
Gene Accssion: NP_776188

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human cytochrome c oxidase assembly homolog 18 (yeast)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total COX18 protein.

Applications:

IHC

Background:

COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain. Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.

References:

appl_detail:

Immunohistochemistry: 1:10-1:50

Datasheet PDF