CEBPA Antibody

Catalog Number:

36789

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P49715
NCBI Gene ID: 1050
Gene Accssion: NP_004355

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human CCAAT/enhancer binding protein (C/EBP), alpha

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CEBPA protein.

Applications:

IHC

Background:

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF