CBX1 Antibody

Catalog Number:

36779

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P83916
NCBI Gene ID: 10951
Gene Accssion: NP_001120700

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human chromobox homolog 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CBX1 protein.

Applications:

IHC

Background:

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression.?

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF