FGF4 Antibody

Catalog Number:

36772

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P08620
NCBI Gene ID: 2249
Gene Accssion: NP_001998

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human fibroblast growth factor 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FGF4 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.

References:

appl_detail:

Immunohistochemistry: 1:50-1:150

Datasheet PDF