LOX Antibody

Catalog Number:

36747

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P28300
NCBI Gene ID: 4015
Gene Accssion: NP_002308

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human Lysyl oxidase

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LOX protein.

Applications:

WB

Background:

The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF