PYGL Antibody

Catalog Number:

36709

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P06737
NCBI Gene ID: 5836
Gene Accssion: BC082229/P06737

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human phosphorylase, glycogen, liver

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PYGL protein.

Applications:

WB IHC

Background:

This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively.?

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:30-1:150

Datasheet PDF