PRC1 Antibody

Catalog Number:

36701

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O43663
NCBI Gene ID: 9055
Gene Accssion: BC003138/O43663

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human protein regulator of cytokinesis 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PRC1 protein.

Applications:

IHC

Background:

This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF