PARP11 Antibody

Catalog Number:

36683

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NR21
NCBI Gene ID: 57097
Gene Accssion: BC017569/Q9NR21

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PARP11 protein.

Applications:

IHC

Background:

Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF