PARL Antibody

Catalog Number:

36682

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9H300
NCBI Gene ID: 55486
Gene Accssion: BC014058/Q9H300

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human presenilin associated, rhomboid-like

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PARL protein.

Applications:

IHC

Background:

This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF