PAICS Antibody

Catalog Number:

36680

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P22234
NCBI Gene ID: 10606
Gene Accssion: BC010273/P22234

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the N terminal of human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PAICS protein.

Applications:

WB IHC

Background:

This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200

Datasheet PDF