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Catalog Number: |
36679 |
| other_names: | PAI; PAI2; PAI-2; PLANH2; HsT1201 |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: P05120 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Fusion protein corresponding to residues near the C terminal of human serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
Purification: |
Antigen affinity purification. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total SERPINB2 protein. |
Applications: |
IHC |
Background: |
Plasminogen activator inhibitor-2?(placental PAI) is a?coagulation?factor that inactivates?tPA?and?urokinase. It is present in most cells, especiallymonocytes/macrophages. PAI-2 exists in two forms, a 60-kDa extracellular glycosylated form and a 43-kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosis during pregnancy. |
References: |
|
appl_detail: |
Immunohistochemistry: 1:25-1:100 |
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