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SERPINB2 Antibody

Catalog Number:

36679
other_names: PAI; PAI2; PAI-2; PLANH2; HsT1201

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P05120
NCBI Gene ID: 5055
Gene Accssion: BC012609/P05120

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human serpin peptidase inhibitor, clade B (ovalbumin), member 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SERPINB2 protein.

Applications:

IHC

Background:

Plasminogen activator inhibitor-2?(placental PAI) is a?coagulation?factor that inactivates?tPA?and?urokinase. It is present in most cells, especiallymonocytes/macrophages. PAI-2 exists in two forms, a 60-kDa extracellular glycosylated form and a 43-kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosis during pregnancy.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

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