OTC Antibody

Catalog Number:

36670

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P00480
NCBI Gene ID: 5009
Gene Accssion: BC107154/P00480

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human ornithine carbamoyltransferase

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total OTC protein.

Applications:

WB IHC

Background:

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.?

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200

Datasheet PDF