KIRREL2 Antibody

Catalog Number:

36653

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q6UWL6
NCBI Gene ID: 84063
Gene Accssion: BC007312/Q6UWL6

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human kin of IRRE like 2 (Drosophila)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KIRREL2 protein.

Applications:

WB

Background:

NEPH3 (nephrin-like protein 3), also referred to as NLG1, FILTRIN or KIRREL2 (kin of IRRE like 2), is a 708 amino acid protein that is a member of the immunoglobulin superfamily of cell adhesion molecules. NEPH3 consists of five extracellular Ig-like repeats, a transmembrane domain, several glycosylation sites and a cytoplasmic domain that has a stretch of nine conserved residues. NEPH3 localizes to the interpodocyte filtration slit in the kidney and to the Langerhans islet beta cells in the pancreas. NEPH3 is thought to be involved in the maintenance of the glomerular filtration barrier in the kidney and in pancreas development.?

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF