Histone H3(mono-methyl-K79) Mouse Monoclonal Antibody (5G5)

Catalog Number:

HW041

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P68431

Form of Antibody:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

A synthetic Mono-methylated peptide corresponding to residues surrounding K79 of human histone H3.

Purification:

Affinity purification using immunogen.

Specificity/Sensitivity:

Antibody detects endogenous Histone H3 (mono-methyl-K79) protein.

Applications:

WB

Background:

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

References:

appl_detail:

Western blotting: 1:500~1:2000

Datasheet PDF