PVRL4 Antibody

Catalog Number:

36647

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96NY8
NCBI Gene ID: 81607
Gene Accssion: BC010423/Q96NY8

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human poliovirus receptor-related 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PVRL4 protein.

Applications:

WB IHC

Background:

This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:300

Datasheet PDF