NDUFAF1 Antibody

Catalog Number:

36637

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9Y375
NCBI Gene ID: 51103
Gene Accssion: BC000780/Q9Y375

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human NADH dehydrogenase (ubiquinone) complex I, assembly factor 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NDUFAF1 protein.

Applications:

WB

Background:

This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19.?

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF