NAT10 Antibody

Catalog Number:

36631

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9H0A0
NCBI Gene ID: 55226
Gene Accssion: BC035558/Q9H0A0

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human N-acetyltransferase 10 (GCN5-related)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NAT10 protein.

Applications:

WB

Background:

NAT-10 (N-acetyltransferase 10) is a nuclear protein that belongs to the UPF0202 family. It has a single N-acetyltransferase domain that likely functions as a histone acetyltransferase. NAT10 functions primarily to regulate the activity of telomerase. It is upregulated in response to DNA damage and is likely to take part in genotoxic resistance and DNA repair. NAT-10 has a high binding potential for the promoter region of TERT which stimulates the production of telomerase. These varieties of function imply that human telomerase complexes have multiple functions rather than specific duties.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF