NANOS2 Antibody

Catalog Number:

36630

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P60321
NCBI Gene ID: 339345
Gene Accssion: BC117484/P60321

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NANOS2 protein.

Applications:

IHC

Background:

Nanos2, also known as NOS2, is a 138 amino acid protein that contains one nanos-type zinc finger. The nanos-type zinc finger is comprised of two C2HC motifs, each of which are capable of binding one molecule of zinc and each of which work in tandem to play essential roles in translational regulation events. Expressed specifically in male germ cells, Nanos2 is essential for spermatogonia formation and is required to support the self-renewal, proliferation and overall development of proximal germ cells. Additionally, Nanos2 is thought to regulate the translation of target mRNAs, possibly by associating with the 3¡¯-UTR of select transcripts.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF