PIDD1 Antibody

Catalog Number:

36588

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9HB75
NCBI Gene ID: 55367
Gene Accssion: BC014904

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the N terminal of human p53-induced death domain protein 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PIDD1 protein.

Applications:

IHC

Background:

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF