ACP6 Antibody

Catalog Number:

36587

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NPH0
NCBI Gene ID: 51205
Gene Accssion: BC034686

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human acid phosphatase 6, lysophosphatidic

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ACP6 protein.

Applications:

WB IHC

Background:

Lysophosphatidic acid phosphatase type 6 (ACP6), also designated acid phosphatase-like protein 1 (ACPL1) or lysophosphatidic acid phosphatase (LPAP), is a 428 amino acid secreted protein that hydrolyzes lysophosphatidic acid to monoacylglycerol. ACP6 is highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and exists as two isoforms as a result of alternative splicing events. The gene encoding ACP6 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease, familial adenomatous polyposis and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200

Datasheet PDF