FCGR3A Antibody

Catalog Number:

36548

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P08637
NCBI Gene ID: 2214
Gene Accssion: BC033678

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FCGR3A protein.

Applications:

IHC

Background:

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF