FGFR1OP Antibody

Catalog Number:

36479

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O95684
NCBI Gene ID: 11116
Gene Accssion: BC011902

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the N terminal of human FGFR1 oncogene partner

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FGFR1OP protein.

Applications:

IHC

Background:

This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.

References:

appl_detail:

Immunohistochemistry: 1:100-1:300

Datasheet PDF