FAIM3 Antibody

Catalog Number:

36458

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60667
NCBI Gene ID: 9214
Gene Accssion: BC006401/O60667

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human Fas apoptotic inhibitory molecule 3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FAIM3 protein.

Applications:

WB IHC

Background:

Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM. May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:20-1:100

Datasheet PDF