EIF3H Antibody

Catalog Number:

36437

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O15372
NCBI Gene ID: 8667
Gene Accssion: BC000386

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human eukaryotic translation initiation factor 3, subunit H

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EIF3H protein.

Applications:

IHC

Background:

Eukaryotic translation initiation factor 3 subunit H?is a?protein?that in humans is encoded by the?EIF3H?gene. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP: methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF