DTNB Antibody

Catalog Number:

36425

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60941
NCBI Gene ID: 1838
Gene Accssion: BC016655

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human dystrobrevin, beta

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DTNB protein.

Applications:

IHC

Background:

This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF