CYBA Antibody

Catalog Number:

36394

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P13498
NCBI Gene ID: 1535
Gene Accssion: NP_000092

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human cytochrome b-245, alpha polypeptide

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CYBA protein.

Applications:

IHC

Background:

Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF