CYP11B1 Antibody

Catalog Number:

36386

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P15538
NCBI Gene ID: 1584
Gene Accssion: BC096285

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human cytochrome P450, family 11, subfamily B, polypeptide 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CYP11B1 protein.

Applications:

IHC

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF