CXCR4 Antibody

Catalog Number:

36326

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P61073
NCBI Gene ID: 7852
Gene Accssion: BC020968

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human chemokine (C-X-C motif) receptor 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CXCR4 protein.

Applications:

IHC

Background:

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF