CARD9 Antibody

Catalog Number:

36309

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9H257
NCBI Gene ID: 64170
Gene Accssion: BC008877

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human caspase recruitment domain family, member 9

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CARD9 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.

References:

appl_detail:

Immunohistochemistry: 1:100-1:300

Datasheet PDF