CARD11 Antibody

Catalog Number:

36308

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BXL7
NCBI Gene ID: 84433
Gene Accssion: BC111719

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human caspase recruitment domain family, member 11

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CARD11 protein.

Applications:

IHC

Background:

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF