CASQ2 Antibody

Catalog Number:

36301

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O14958
NCBI Gene ID: 845
Gene Accssion: BC022288

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human calsequestrin 2 (cardiac muscle)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CASQ2 protein.

Applications:

IHC

Background:

The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF