PTK6 Antibody

Catalog Number:

36291

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q13882
NCBI Gene ID: 5753
Gene Accssion: BC035843

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human protein tyrosine kinase 6

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PTK6 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF