ANKHD1 Antibody

Catalog Number:

36259

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8IWZ3
NCBI Gene ID: 54882
Gene Accssion: BC009420

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human ankyrin repeat and KH domain containing 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ANKHD1 protein.

Applications:

IHC

Background:

This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF