ABI3BP Antibody

Catalog Number:

36249

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q7Z7G0
NCBI Gene ID: 25890
Gene Accssion: BC030221

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human ABI family, member 3 (NESH) binding protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ABI3BP protein.

Applications:

IHC

Background:

A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF