ASB8 Antibody

Catalog Number:

36241

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9H765
NCBI Gene ID: 140461
Gene Accssion: BC001321

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the N terminal of human ankyrin repeat and SOCS box containing 8

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ASB8 protein.

Applications:

IHC

Background:

ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF