ASB2 Antibody

Catalog Number:

36263

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96Q27
NCBI Gene ID: 51676
Gene Accssion: BC032354

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human ankyrin repeat and SOCS box containing 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ASB2 protein.

Applications:

IHC

Background:

This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF