NPPB Antibody

Catalog Number:

36213

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P16860
NCBI Gene ID: 4879
Gene Accssion: BC025785

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human natriuretic peptide B

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NPPB protein.

Applications:

IHC

Background:

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF