RICTOR Antibody

Catalog Number:

36195

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q6R327
NCBI Gene ID: 253260
Gene Accssion: BC029608

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RICTOR protein.

Applications:

IHC

Background:

Rapamycin-insensitive companion of mTOR?is a?protein?that in humans is encoded by the?RICTOR?gene. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.

References:

appl_detail:

Immunohistochemistry: 1:25-1:200

Datasheet PDF